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KMID : 0363020140440040207
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Journal of Korean Academy of Periodontology
2014 Volume.44 No. 4 p.207 ~ p.213
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Micronutrients and superoxide dismutase in postmenopausal women with chronic periodontitis: a pilot interventional study
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Daiya Sunita
Sharma Rajinder Kumar
Tewari Shikha
Narula Satish Chander
Sehgal Paramjeet Kumar
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Abstract
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Purpose: The study was aimed at investigating changes in periodontal parameters and superoxide dismutase activity triggered by root surface debridement with and without micronutrient supplementation in postmenopausal women.
Methods: Forty-three postmenopausal chronic periodontitis patients were divided into two groups: group 1 (n=22) were provided periodontal treatment in the form of scaling and root planing (SRP) and group 2 (n=21) patients received SRP along with systemic administration of micronutrient antioxidants. Patients in both groups were subjected to root surface debridement. Group 2 patients also received adjunctive micronutrient antioxidant supplementation. Serum and salivary superoxide dismutase (SOD) activity along with periodontal parameters were recorded at baseline and 3 months after therapy.
Results: Salivary and serum SOD values significantly (P<0.05) improved with periodontal treatment. Improvement in systemic enzymatic antioxidant status along with reduction in gingival inflammation and bleeding on probing (%) sites was significantly greater in group 2 as compared to group 1.
Conclusions: Adjunctive micronutrient supplements reduce periodontal inflammation and improve the status of systemic enzymatic antioxidants in postmenopausal women.
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KEYWORD
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Antioxidants , Clinical trial , Chronic periodontitis , Root planning
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